StarT project
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ESR1
- Partner 4 (TIGEM): Identification of the gene networks that modulate ABCA4 expression
ESR2
- Partner 6 (CSIC): Interaction map of cis-regulatory elements controlling ABCA4 in human retina
ESR3
- Partner 1 (UGent): Mapping the cis-regulatory landscape of ABCA4 in adult human retina
ESR4
- Partner 1 (UGent): Functional assessment of a cis-regulatory element of ABCA4 in a frog model
ESR5
- Partner 2 (RUMC): Identification and splice assays of deep-intronic ABCA4 variants in mono-allelic STGD1
ESR6
- Partner 5 (UNIVLEEDS): Long-read sequencing of the ABCA4 locus
ESR7
- Partner 1 (UGent): Identification and characterisation of structural variants and non-coding sequence variants of ABCA4
ESR8
- Partner 9 (NewCells): ABCA4 transcript analysis of retinal cells derived from mono-allelic STGD1 cases
ESR9
- Partner 2 (RUMC): Antisense oligonucleotide-based splice modulation for deep-intronic mutations in ABCA4
ESR10
- Partner 10 (ProQR): Optimisation, delivery and tolerability of antisense oligonucleotides to treat STGD1 patients with the most common splice mutation in ABCA4
ESR11
- Partner 4 (TIGEM): ABCA4 knockout pig as model for gene therapy in STGD1
ESR12
- Partner 3 (EKUT): CRISPR/Cas9 gene editing for excision and rescue of deep-intronic mutations in ABCA4
ESR13
- Partner 7 (TCD): AAV vector delivery targeting common pathways of disease in STGD1
ESR14
- Partner 8 (UCL): Pharmacological protein folding manipulation of ABCA4 mutations
StarT project
ESR PROFILES
Partners
papers
News
Agenda
Contact